Reparil Coated Tablets
This data sheet conforms in all essential parts with the user information as prescribed by law in Germany.
Inhibit oedema, reduce swelling, inhibit inflammation
Composition
1 coated tablet contains:
Aescin amorphosed 20 mg.
Adjuvants: polyvidone, magnesium stearate, talc, gum arabic, poly(ethyl acrylate, methacrylic acid), Macrogol 8000, sodium hydroxide, carmellose sodium, triethyl citrate, dimethicone, titanium dioxide, lactose, colloidal silicon dioxide, sucrose, natural waxes.
Uses
Swelling following injuries, headaches following concussion, for supportive treatment in cases of tendinitis (inflammation of tendon sheaths), for continuing Reparil treatment initiated intravenously.
Contraindications
As a precaution, Reparil coated tablets should not be used during the first 3 months of pregnancy except under a doctor's explicit instructions.
Side effects
In occasional instances, there may be some disturbance of gastric or intestinal function. Hypersensitivity reactions such as urticaria may arise in isolated cases.
Interactions with other drugs
The action of anticoagulants may be potentiated by Reparil coated tablets.
Dosage guidance and mode of administration
Unless otherwise directed, start with an initial dose of 2 coated tablets 3 times daily. As a maintenance dose and in milder cases, take 1 coated tablet 3 times daily with some liquid after meals.
Dosage for children:
Take 1 coated tablet 2 - 3 times daily with some liquid after meals.
Properties
Aescin, the active agent of horse chestnut, acts by dispersing swelling, removing excess fluid and inhibiting inflammation. It exerts these effects at the site of the disorder, thus rapidly alleviating symptoms (such as sensations of pressure, pain, etc) caused by local swelling. It has no adverse effects on mineral metabolism or the blood forming system.
Presentation and pack sizes:
Packs of 20, 50 and 100 coated tablets
M. No. 212054/12.95
What is aescin?
Aescin is the active ingredient of Reparil, and is extracted from horse chestnut seeds (Aesculus hippocastanum). Extracts of horse chestnut have long been used in folk medicine for the treatment of vein disorders and haemorrhoids. Scientific research began towards the end of the nineteenth century. Aescin acts mainly by preventing or reducing swelling, by blocking inflammation and also by heightening venous tone.
When can Reparil be employed?
Reparil can in general be employed for all painful conditions of the locomotor system. Among these are blunt injuries, sprains, contusions, strains, torn muscles, inflammation of tendon sheaths, varicose veins, swollen legs, etc.
Can a product containing an active substance of plant origin really be of lasting help in serious injuries and inflammatory conditions?
Numerous large-scale clinical trials have provided evidence that Reparil, because of its combination of active ingredients, is clearly superior to other remedies. Its action is rapid and long-lasting, it promotes regenerative activity and thereby exercises a healing effect.
What about adverse effects?
In all trials Reparil Gel N was assessed as extremely well tolerated. In occasional cases, there may be some drying of the skin and scaling after prolonged treatment. Fatty acids are included in the formulation to protect the skin.
Aescin DEAS gels have been used by millions of patients for more than 20 years. Cases of contact allergy are extremely rare (in less than 0.01% of cases).
There has never been any evidence of systemic side effects. This implies that aescin remains at the site where it is applied, and is broken down locally.